Research Initiatives Conference

Provided by the
Society for Vascular Surgery®

Research Initiatives in Vascular Disease Conference

April 7, 2010   |   Hilton San Francisco   |   San Francisco, California

Registration   

Click here to register online.

You also can register by downloading the registration form. Return the completed form via mail to Society for Vascular Surgery®, 38678 Eagle Way, Chicago, IL 60678-1386 or via fax to 312-334-2320 (credit card only).

View the cancellation policy.   

Program Overview   

The Research Initiatives in Vascular Disease Conference is specifically designed to encourage interaction between vascular surgeon investigators and scientists from other vascular biology-related disciplines. A particular objective is to stimulate interest in research among trainees who are aspiring academic vascular surgeons.

Learning Objectives   

At the end of this session, participants should be able to:

Awardee Reports

  1. Discuss kidney-lung interactions during ischemia-reperfusion injury.
  2. Describe endothelial function during peripheral vein bypass graft remodeling.

Session I: Toward a Better Model of Peripheral Arterial Disease - Chronic Disease

  1. Discuss the current use of animal models elucidating the pathophysiology of chronic peripheral arterial disease.
  2. Identify new areas of basic and methodological research in chronic peripheral arterial disease.
  3. Describe new venues of current clinical and translational research in chronic peripheral arterial disease.

Session II: Toward a Better Model of Peripheral Arterial Disease - Acute Disease, Ischemia/Reperfusion

  1. Discuss the current use of animal models elucidating the pathophysiology of acute peripheral arterial disease.
  2. Identify new areas of basic and methodological research in acute peripheral arterial disease.
  3. Describe new venues of current clinical and translational research in acute peripheral arterial disease.

Session III: Vascular Endothelium and Thrombosis

  1. Discuss the current use of animal models elucidating the pathophysiology of thrombosis and venous disease.
  2. Identify new areas of basic and methodological research in thrombosis and venous disease.
  3. Describe new venues of current clinical and translational research in thrombosis and venous disease.

Session IV: Aneurysms

  1. Discuss the current use of animal models elucidating the pathophysiology of aneurysmal disease.
  2. Identify new areas of basic and methodological research in aneurysmal disease.
  3. Describe new venues of current clinical and translational research in aneurysmal disease.

Who Should Attend?   

The Research Initiatives in Vascular Disease Conference brings together vascular surgeons, vascular biologists, physicians with an interest in vascular problems, vascular surgery trainees, research trainees in vascular surgery and vascular biology, industry personnel with an interest in vascular disease. 

Continuing Medical Education (CME) Credit   

The Society for Vascular Surgery (SVS) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The SVS designates this educational activity for a maximum of 6.5 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Program Schedule   

Program is subject to change.

Wednesday, April 7, 2010

7:30 am

Registration and Continental Breakfast

8:00 am

Introductory Remarks
Alan Dardik, MD, PhD
Robert Hegele, MD, FAHA
Murray W. Huff, PhD, FAHA

8:10 am

KO8 Awardee Report
“Kidney-Lung Interactions During Ischemia-Reperfusion Injury”
Heitham T. Hassoun, MD
Methodist Hospital Physician Organization & DeBakey Heart & Vascular Center, Houston, TX

8:20 am

K23 Awardee Report
“Endothelial Function and Peripheral Vein Bypass Graft Remodeling”
Christopher D. Owens, MD
University of California San Francisco, San Francisco, CA

8:30 am

Session I: Toward a Better Model of Peripheral Arterial Disease – Chronic Disease

Moderators: Iraklis I. Pipinos, MD and Catherine A. Reardon, PhD

8:30 am
Mesenchymal Stem Cell Dysfunction in Response to Hind limb Ischemia in Type 2 Diabetic Mice
Louis M. Messina, MD
University of Massachusetts Medical School, Worcester, MA

Research Paper Presentations

9:00 am
Venous Specific Eph-B4 Regulates Vein Graft Thickening Via Caveolin-1
Akihito Muto, Tai Yi, Kenneth Harrison, Alberto Davalos, William C. Sessa, Alan Dardik
Yale University School of Medicine, New Haven, CT

9:15 am
Short-term Diet Induced Obesity Drives Negative Vein Graft Remodeling
Peng Yu, Binh Nguyen, Ming Tao, Christina Campagna, James A. Lederer, C. K. Ozaki
Surgery, Brigham and Women's Hospital/Harvard Medical School, Boston, MA

9:30 am
Vascular Smooth Muscle Enhances Functionality of Tissue Engineered Blood Vessels in Vivo
Lucas P. Neff(1), Bryan Tillman(1), Saami Yazadani(2), Masood Machingal(2), James Yoo(2), Shay Soker(2), Brian Bernish(1), Randolph Geary(1), George Christ(2)
(1)Vascular Surgery, Wake Forest University School of Medicine, Winston-Salem, NC; (2)Wake Forest Institute of Regenerative Medicine, Winston-Salem, NC

9:45 am
Durable Effect of Nitric Oxide at Inhibiting Neointimal Hyperplasia is due to Modulation of Cellular Populations Throughout the Arterial Wall
Ashley Vavra, Janet Martinez, Vanessa R. Lee, Bo Fu, Qun Jiang, Melina R. Kibbe
Division of Vascular Surgery, Northwestern University, Chicago, IL

10:00 am

Coffee Break

10:30 am

Session II: Toward a Better Model of Peripheral Arterial Disease - Acute Disease, Ischemia/Reperfusion

Moderators: Raul J. Guzman, MD and Steven R. Lentz, MD, PhD, FAHA

10:30 am
CCR2-activating Chemokines in Arteriogenesis, Angiogenesis and Skeletal Muscle Regeneration
Paula Shireman, MD
University of Texas Health Sciences Center, San Antonio, TX

Research Paper Presentations

11:00 am
Toll-like Receptors 2 and 4, But Not RAGE Deficiency Results in Greater Muscle Necrosis 2 Weeks After Hind-limb Ischemia: Implications for Muscle Recovery After Ischemic Injury
Ulka Sachdev, Xiangdong Cui, Tian Wang, Edith Tzeng
Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA

11:15 am
Differential Expression of ERK and Akt Following Nitric Oxide Exposure in Type 1 and Type 2 Diabetic Rats
Zachary Emond, Vinit Varu, Sadaf Ahanchi, Janet Martinez, Melina R. Kibbe
Vascular Surgery, Northwestern University, Chicago, IL

11:30 am
Cytostatic Gene Therapy: RNAi-mediated Survivin Knockdown Induces Cell Cycle Arrest, Polyploidy, and Reduced Migration of Vascular Smooth Muscle Cells (VSMC)
Christoph S. Nabzdyk, Hope Lancero, Khanh P. Nguyen, Sherveen Salek, Michael S. Conte
Division of Vascular Surgery, University of California San Francisco, San Francisco, CA

11:45 am
Surgical Restoration of Flow Following Prolonged Ischemia Inhibits Neuromuscular Recovery in a Porcine (Sus Scrofa) Model of Extremity Vascular Injury
Gabriel Burkhardt(1), Shaun Gifford(2), Brandon Propper(2), Jerry Spencer(2), Ken Williams(2), Lyell Jones(2), Nathan Sumner(2), Jerry Cowart(2), Todd E. Rasmussen(3)
(1)University of Texas Health Science Center at San Antonio, San Antonio, TX; (2)San Antonio Military Medicine Center Consortium Wilford Hall USAF Medical Center, the 59th Clinical Research Squadron, and Genesis Concepts & Consultants under USAF Contract No: FA7014-09-D-0008, San Antonio, TX; (3)The Uniformed Services University of the Health Sciences,
Bethesda, MD

Noon

Lunch

1:30 pm

Session III: Vascular Endothelium and Thrombosis

Moderators: Eva M. Rzucidlo, MD and Nigel Mackman, PhD

1:30 pm
The Use of Animal Models in Venous Thrombosis Research
Thomas W. Wakefield, MD
University of Michigan Medical Center, Ann Arbor, MI

Research Paper Presentations

2:00 pm
A Novel In Vitro Model of Chronic Venous Insufficiency
Carolyn Glass, John Cullen, Yanji Qi, Elisa Roztocil, Michael Singh, Karl Illig, David Gillespie
Division of Vascular Surgery, University of Rochester, Rochester, NY

2:15 pm
Novel Target for the Regulation of Post-Natal Neovascularization in the Setting of Diabetic Wound Healing
Zhao-Jun Liu, Runxia Tian, Ying Zhuge, Yan Li, Hongwei Shao, Weijun An, Bianca Habib, Alan S. Livingstone, Omaida C. Velazquez
DeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL

2:30 pm
A Specific Inhibitor of IGF-1 Receptor - Picropodophyllin Can Suppress Atheroma Progression and Has a Stabilizing Effect on Atherosclerotic Lesions in ApoE Deficient Mice
Anton Razuvaev, Olle Larsson, Magnus Axelson, Ulf Hedin, Joy Roy
Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

2:45 pm
Expression of the Heat Shock Protein HSPB1 Is Associated with Impaired Smooth Muscle Relaxation
Syed Z. Rizvi, Kyle M. Hocking, Erica Morley, Padmini Komalavilas, Joyce Cheung-Flynn, Colleen M. Brophy
Vascular Surgery, Vanderbilt University Medical Center, Nashville, TN

3:00 pm 

Coffee Break

3:30 pm

Session IV: Aneurysms

Moderators: John A. Curci, MD, FACS and Alan Daugherty, PhD, DSc, FAHA

3:30 pm
What I Don’t Know About Abdominal Aortic Aneurysms
Robert W. Thompson, MD
Washington University, St. Louis, MO

Research Paper Presentations

4:00 pm
Ethyl Pyruvate Prevents Delayed Paralysis In a Murine Model of Spinal Cord Ischemic Injury
Bao-Ngoc H. Nguyen, Hassan Albadawi, Robert S. Crawford, Hyung-Jin Yoo, Mark F. Conrad, Richard P. Cambria, Michael T. Watkins
Division of Vascular and Endovascular Surgery--Massachusetts General Hospital & Harvard Medical School, Boston, MA

4:15 pm
Estrogen Stimulates the Cellular Processes of Intimal Hyperplasia Development Via ERK1/2 Dependent Signaling Cascades
Deidra J. Mountain, Mike Tummers, Stacy S. Kirkpatrick, David C. Cassada, Scott L. Stevens, Michael B. Freeman, Mitchell H. Goldman, Oscar Grandas
Department of Surgery, University of Tennessee Graduate School of Medicine, Knoxville, TN

4:30 pm
Effect of Remote Ischemic Preconditioning in Liver Ischemia - Reperfusion Injury Produced By Supraceliac Aortic Cross-clamping in a Swine Model of Open Repair of Thoracoabdominal Aortic Aneurysm
Andreas M. Lazaris(1), Georgios Martikos(1), Alkistis Kapelouzou(2), Katerina Pavlaki(2), Michalis Peroulis(1), John Kakisis(1), Spyros Vasdekis(1), Panagiotis Karagiannakos(2), Gabriel Karatzas(1), Anastasios Maheras(1), Alkiviadis Kostakis(2), Theodore Liakakos(1)
(1)3rd Surgical Department, University of Athens, Attikon Teaching Hospital, Athens, Greece; (2)Biomedical Research Foundation, Academy of Athens, Department of Surgery, Athens, Greece

4:45 pm
An Aortic Model for Physiological Assessment of Aortic Stent-grafts and in Vitro Compliance Measurement
Mital Y. Desai(1), Max Ahmed(1), Arnold Darbyshire(1), Alexander Seifalian(1), George Hamilton(2)
(1)University College London Division of Surgery and Interventional Science, Royal Free Hospital, London, United Kingdom; (2)Vascular Surgery, Royal Free Hampstead NHS Trust, London, United Kingdom

5:00 pm

Reception

Course Director   

Alan Dardik, MD, PhD
Yale University School of Medicine, New Haven, CT

Faculty   

Heitham T. Hassoun, MD
Methodist Hospital Physician Organization & DeBakey Heart & Vascular Center, Houston, TX

Robert Hegele, MD, FAHA
University of Western Ontario, London, Ontario, Canada

Murray W. Huff, PhD, FAHA
University of Western Ontario, London, Ontario, Canada

Louis M. Messina, MD
University of Massachusetts Medical School, Worcester, MA

Christopher D. Owens, MD
University of California San Francisco, San Francisco, CA

Paula Shireman, MD
University of Texas Health Sciences Center, San Antonio, TX

Robert W. Thompson, MD
Washington University, St. Louis, MO

Thomas W. Wakefield, MD
University of Michigan Medical Center, Ann Arbor, MI

Moderators

John A. Curci, MD, FACS
Washington University School of Medicine, St Louis, MO

Alan Daugherty, PhD, DSc, FAHA
University of Kentucky, Lexington, KY

Raul J. Guzman, MD
Vanderbilt University Medical Center, Nashville, TN

Steven R. Lentz, MD, PhD, FAHA
University of Iowa, Iowa City, IA

Nigel Mackman, PhD
University of North Carolina at Chapel Hill, Chapel Hill, NC

Iraklis I. Pipinos, MD
University of Nebraska Medical Center, Omaha, NE

Catherine A. Reardon, PhD
University of Chicago, Chicago, IL

Eva M. Rzucidlo, MD
Dartmouth Hitchcock Medical Center, Lebanon, NH

Faculty Disclosure   

Disclosure statements have been requested from the faculty and will be made available at the conference. SVS also requires that all faculty presenters are also expected to disclose to participants any discussions of off-label and/or investigational uses of pharmaceutical products and/or medical devices during their presentations.

SVS Staff Disclosure

Disclosure statements have been requested from all SVS staff members. SVS staff members have nothing to disclose.

Hotel Reservations   

The Hilton San Francisco Union Square Hotel is pleased to host the Research Initiatives in Vascular Disease Conference. With the best of San Francisco at its doorstep, the Hilton San Francisco offers attendees access to the city’s most sought after cultural and attractions. With its premier location within the heart of the city, you will be within walking distance to some of the most famous San Francisco neighborhoods including China Town, Nob Hill, the famous cable cars, shopping, dining and much more. The Hilton offers the following:

  • Hilton Suite Dreams Bedding which features a plush-top mattress and fine European-style linens
  • Nourish by Spa Chakra – Full Service spa
  • A full service business centerSuites and guestrooms with stunning views of the city
  • Concierge services
  • Delicious dining at The Urban Tavern and the best on-the-go beverages at Starbucks
  • High-speed Internet access in all guestrooms
  • Tower City View Rooms – Feature an upgraded sleeping room, amenities and a continental breakfast at Starbucks along with complimentary high-speed Internet access

A block of guest rooms has been reserved for attendees of the Research Initiatives Conference. The special group rate of $239/night*, single/double occupancy, is available on a first-come, first-served basis until March 23, 2010 or until the block sells out, whichever comes first. The conference rate is available for hotel stays from April 3 through April 11 based on availability. Click here or call Hilton Reservations Worldwide at 800-445-8667 or by calling the Hilton Bay Area Regional Reservation desk at 415-771-1400 (choose option “1” for reservations) to make your reservations.  Be sure to identify yourself as part of the Society for Vascular Surgery Research Initiatives Conference.

* Subject to applicable state, local and occupancy tax, currently at 15.58 percent.

Hotel Address
Hilton San Francisco Union Square Hotel
333 O’Farrell Street
San Francisco, CA 94102

  • Reservations may be made online
  • Reservations may be made by calling Hilton Reservations Worldwide toll free at 800-445-8667. International guests may call 415-771-1400
  • Reservations must be guaranteed with a major credit card (American Express, Carte Blanche, Diners Club, Visa, or MasterCard)
  • Cancellations will be accepted 48 hours prior to arrival
  • Check-in time is 3:00 pm; check-out time is Noon, after Noon additional charges will apply

Arteriosclerosis, Thrombosis and Vascular Biology 2010 Scientific Sessions   

SVS attendees are invited to attend the ATVB 2010 Scientific Sessions, being held April 8-10, 2010. Special lectures, discussion and oral and poster presentations are planned. The meeting format is designed to provide opportunities for intense interaction among participants. A broad representation from many disciplines is expected, and young scientists are encouraged to attend. SVS registrants who wish to attend the ATVB meeting will receive a $100 discount off registration. Additional information and the preliminary program/call for abstracts may be found at the conference Web site.

Cancellation Policy   

Requests for refunds/cancellations for the Research Initiatives in Vascular Disease Conference must be received in writing by Wednesday, March 24, 2010. No refunds will be given after that date. Refunds will be subject to a $50 cancellation fee.

SVS reserves the right to cancel or postpone courses due to unforeseen circumstances. In this event, a full registration refund will be given, but SVS is not responsible for any related charges or expenses to participants, including fees assessed by hotels, airlines, or travel agencies. 

Questions

Please call 800-258-7188 or email education@vascularsociety.org if you have questions.

Please note: We cannot control the temperature in the meeting rooms, so please dress accordingly.

Society for Vascular Surgery - 633 N. St. Clair, 24th Floor; Chicago, IL 60611; Phone: 312-334-2300 or 800-258-7188; Fax: 312-334-2320; Email: vascular@vascularsociety.org
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