Kei Ichihashi, Yoshimitsu Soga
Cardiology, Kokura Memorial Hospital, Fukuoka, Japan.
OBJECTIVES: The purpose of this study is to evaluate the gender differences in the long-term outcomes of infrainguinal revascularization in multicenter experience.
METHODS: This study was multicenter retrospective analysis from January 2004 to December 2009. 1,001 limbs (696 men, Group 1; and 305 women, Group 2) underwent infrainguinal arterial revascularization; endovascular therapy and bypass surgery. Male and female group were compared in terms of primary patency and secondary patency. Patencies were assessed by either duplex ultrasound or angiography, analyzed by Kaplan-Meier estimation and compared by the log rank test.
RESULTS: There were no differences in all cause death, MACE and MALE between two groups. At 6 years, the primary patency rate were 48.2% (male group) and 32.1% (female group) (p=0.0001), secondary patency rates were 80.5% and 68.9% (p=0.0008). Gender (HR1.40; 95% CI 1.15 to 1.73, p=0.001) and critical limb ischemia (HR 1.61; 95% CI 1.16 to 2.23) were risk factors of infrainguinal artery restenosis.
Significant sex differences exist with regard to the outcomes in infrainguinal arterial revascularization.
Posted April 2013